基因名：
PSMD11
产品别名：
Rpn6； S9； p44.5； PSMD11； proteasome 26S subunit, non-ATPase 11； proteasome 26S subunit, non-ATPase 11； 26S proteasome non-ATPase regulatory subunit 11； 26S proteasome regulatory subunit 9； 26S proteasome regulatory subunit RPN6； 26S proteasome regulatory subunit S9； 26S proteasome regulatory subunit p44.5； proteasome (prosome, macropain) 26S subunit, non-ATPase, 11； 26S蛋白酶体非ATP酶调节亚基11；
背景信息：
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a member of the proteasome subunit S9 family that functions as a non-ATPase subunit of the 19S regulator and is phosphorylated by AMP-activated protein kinase. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jul 2012]
