基因名：
PSMD9
产品别名：
Rpn4； p27； PSMD9； proteasome 26S subunit, non-ATPase 9； proteasome 26S subunit, non-ATPase 9； 26S proteasome non-ATPase regulatory subunit 9； 26S proteasome regulatory subunit p27； homolog of rat Bridge 1； proteasome (prosome, macropain) 26S subunit, non-ATPase, 9； proteasome 26S non-ATPase regulatory subunit 9； 蛋白酶调解因子9； 非ATP酶蛋白酶体26S亚基9(PSMD9)；
背景信息：
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, May 2012]
