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重组26S蛋白酶调节亚型S5a
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。

重组非ATP酶蛋白酶体26S亚基4(PSMD4)
Recombinant PSMD4
基因名:

PSMD4


产品别名:

AF; AF-1; ASF; MCB1; Rpn10; S5A; pUB-R5; PSMD4; proteasome 26S subunit ubiquitin receptor, non-ATPase 4; proteasome 26S subunit ubiquitin receptor, non-ATPase 4; 26S proteasome non-ATPase regulatory subunit 4; 26S proteasome regulatory subunit S5A; S5a/antisecretory factor protein; angiocidin; antisecretory factor 1; multiubiquitin chain-binding protein; proteasome (prosome, macropain) 26S subunit, non-ATPase, 4; proteasome 26S subunit, non-ATPase 4; 26S蛋白酶调节亚型S5a; 非ATP酶蛋白酶体26S亚基4(PSMD4);


背景信息:
S5a is one of the integral Ub receptors of the 26S proteasome. It’s N-terminal vWA domain interacts with Rpn9 and Rpn10 on the 26S proteasome. The C-terminal domain of S5a contains two Ub-interacting motifs (UIMs) that bind Ub and Ub chains. S5a prefers to bind polyUb chains; it also binds proteins containing a Ub-like domain. It may directly recognize ubiquitinated proteins or coordinate with other Ub receptors to target substrates for proteasomal degradation.
 
 
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