基因名：
MAPK11
产品别名：
P38B； P38BETA2； PRKM11； SAPK2； SAPK2B； p38-2； p38Beta； MAPK11； mitogen-activated protein kinase 11； mitogen-activated protein kinase 11； mitogen-activated protein kinase 11； MAP kinase 11； MAP kinase p38 beta； mitogen-activated protein kinase p38 beta； mitogen-activated protein kinase p38-2； stress-activated protein kinase-2； stress-activated protein kinase-2b； 丝裂原活化的蛋白激酶p38β； 丝裂原激活蛋白激酶11(MAPK11)； 磷酸化丝裂原活化的蛋白激酶p38β；
背景信息：
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. MAPK11 is most closely related to p38 MAP kinase, both of which can be activated by proinflammatory cytokines and environmental stress. This kinase is activated through its phosphorylation by MAP kinase kinases (MKKs), preferably by MKK6. Transcription factor ATF2/CREB2 has been shown to be a substrate of this kinase.
