基因名：
PKN2
产品别名：
PAK2； PRK2； PRKCL2； PRO2042； Pak-2； STK7； PKN2； protein kinase N2； protein kinase N2； serine/threonine-protein kinase N2； PKN gamma； cardiolipin-activated protein kinase Pak2； protein kinase C-like 2； protein-kinase C-related kinase 2； 蛋白激酶N2； 蛋白激酶N2(PKN2)；
背景信息：
Protein-kinase-C-related kinases (PRKs) are part of the lipid-regulated protein kinases (PKC) which also include liver PAK & PKN. Human PRK1 and PRK2 share structurally similar catalytic domains, but less similar N-terminal regulatory regions suggesting different regulatory domain functions. PRK1 and PRK2, as well as a third member of this family, PRK3, show distinct patterns of expression in adult tissues. Additionally, the serine-threonine kinase PRK2 can be specifically cleaved by caspase-3 (and/or caspase-3-like subfamily members) during apoptosis
