基因名：
PRKAG1
产品别名：
AMPKG； PRKAG1； protein kinase AMP-activated non-catalytic subunit gamma 1； protein kinase AMP-activated non-catalytic subunit gamma 1； 5'-AMP-activated protein kinase subunit gamma-1； 5'-AMP-activated protein kinase, gamma-1 subunit； AMPK gamma-1 chain； AMPK gamma1； protein kinase, AMP-activated, gamma 1 non-catalytic subunit； AMP激活蛋白激酶γ1(PRKAg1)； 腺苷酸活化蛋白激酶γ1；
背景信息：
The 5 AMP activated protein kinase (AMPK), a member of the SNF1 (sucrose non fermentor) kinase family, is a heterotrimeric protein comprise of alpha (63 kDa), beta (30 kDa) and gamma (38 kDa) subunits. The alpha subunit is the catalytic subunit, while beta and gamma are non catalytic subunits (although they have been found to interact with the active subunit in liver). AMPK regulates fatty acid and sterol synthesis by phosphorylation of acetyl CoA as well as cholesterol synthesis via phosphorylation and inactivation of hydroxymethylglutaryl CoA reductase. AMPK is activated by AMP and can be also regulated by treatment with purified protein phosphatase in vitro.
