基因名:
PKIB
产品别名:
PRKACN2; PKIB; cAMP-dependent protein kinase inhibitor beta; cAMP-dependent protein kinase inhibitor beta; cAMP-dependent protein kinase inhibitor beta; PKI-beta; cAMP-dependent protein kinase inhibitor 2; protein kinase (cAMP-dependent, catalytic) inhibitor beta; 蛋白激酶抑制因子β(PKIb); 蛋白激酶抑制蛋白β;
背景信息:
cAMP-Dependent Protein Kinase Inhibitor β (PKI-β) is a member of the PKI family. As a member of the cAMP-dependent protein kinase inhibitor family,It has been shown that PKI-β is an extremely potent competitive inhibitor of cAMP-dependent protein kinase activity; this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains. It may play a role in the protein kinase A (PKA) pathway by interacting with the catalytic subunit of PKA, and overexpression of this gene may play a role in prostate cancer.