基因名:
PPP1CA
产品别名:
PP-1A; PP1A; PP1alpha; PPP1A; PPP1CA; protein phosphatase 1 catalytic subunit alpha; protein phosphatase 1 catalytic subunit alpha; serine/threonine-protein phosphatase PP1-alpha catalytic subunit; protein phosphatase 1, catalytic subunit, alpha isozyme; serine/threonine protein phosphatase PP1-alpha 1 catalytic subunit; testicular tissue protein Li 155; 蛋白磷酸酶1催化亚基α亚型(PPP1Ca); 蛋白磷酸酶2Cα;
背景信息:
PPP1A is a serine/threonine protein phosphatase catalytic subunit that is essential for regulating cellular stress responses in eukaryotes. It binds to magnesium or manganese ions and exists as a monomer. It is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. PPP1A is involved in the regulation long term synaptic plasticity and may play an important role in dephosphorylating substrates such as Ca2+/calmodulin dependent protein kinase II.