基因名：
PMAIP1
产品别名：
APR； NOXA； PMAIP1； phorbol-12-myristate-13-acetate-induced protein 1； phorbol-12-myristate-13-acetate-induced protein 1； phorbol-12-myristate-13-acetate-induced protein 1； PMA-induced protein 1； adult T cell leukemia-derived PMA-responsive； immediate-early-response protein APR； protein Noxa； Noxa蛋白；
背景信息：
Promotes activation of caspases and apoptosis. Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1. Competes with BAK1 for binding to MCL1 and can displace BAK1 from its binding site on MCL1 (By similarity). Competes with BIM/BCL2L11 for binding to MCL1 and can displace BIM/BCL2L11 from its binding site on MCL1.
