基因名:
PLG
产品别名:
HAE4; PLG; plasminogen; plasminogen; plasminogen; plasmin; 纤溶酶原(Plg); 纤溶酶原(Plg)天然蛋白; 纤溶酶原(Plg)真核蛋白; 纤维蛋白溶酶原;
背景信息:
The protein encoded by this gene is a secreted blood zymogen that is activated by proteolysis and converted to plasmin and angiostatin. Plasmin dissolves fibrin in blood clots and is an important protease in many other cellular processes while angiostatin inhibits angiogenesis. Defects in this gene are likely a cause of thrombophilia and ligneous conjunctivitis. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Dec 2009]