基因名：
PFKP
产品别名：
ATP-PFK； PFK-C； PFK-P； PFKF； PFKP； phosphofructokinase, platelet； phosphofructokinase, platelet； ATP-dependent 6-phosphofructokinase, platelet type； 6-phosphofructokinase type C； 6-phosphofructokinase, platelet type； phosphofructo-1-kinase isozyme C； phosphofructokinase 1； phosphohexokinase； 6-磷酸果糖激酶C； 血小板型磷酸果糖激酶(PFKP)；
背景信息：
The PFKP gene encodes the platelet isoform of phosphofructokinase (PFK) (ATP:D-fructose-6-phosphate-1-phosphotransferase, EC 2.7.1.11). PFK catalyzes the irreversible conversion of fructose-6-phosphate to fructose-1,6-bisphosphate and is a key regulatory enzyme in glycolysis. The PFKP gene, which maps to chromosome 10p, is also expressed in fibroblasts. See also the muscle (PFKM; MIM 610681) and liver (PFKL; MIM 171860) isoforms of phosphofructokinase, which map to chromosomes 12q13 and 21q22, respectively. Vora (1981) [PubMed 6451249] determined that full tetrameric phophofructokinase enzyme expressed in platelets can be composed of subunits P4, P3L, and P2L2.[supplied by OMIM, Mar 2008]
