基因名：
PFKFB2
产品别名：
PFK-2/FBPase-2； PFKFB2； 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2； 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2； 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2； 6PF-2-K/Fru-2,6-P2ASE heart-type isozyme； 6PF-2-K/Fru-2,6-P2ase 2； PFK/FBPase 2； PFKFB, cardiac； fructose-2,6-bisphosphatase, cardiac isozyme； 果糖-2,6-二磷酸酶2/磷酸果糖激酶2；
背景信息：
PFKFB2 is involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. It has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate, and a fructose-2,6-biphosphatase activity that catalyzes the degradation of fructose-2,6-bisphosphate. PFKFB2 regulates fructose-2,6-bisphosphate levels in the heart, while a related enzyme encoded by a different gene regulates fructose-2,6-bisphosphate levels in the liver and muscle. This enzyme functions as a homodimer. There are two named isoforms.
