基因名：
PDK1
产品别名：
PDK1； pyruvate dehydrogenase kinase 1； pyruvate dehydrogenase kinase 1； [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial； pyruvate dehydrogenase (acetyl-transferring) kinase isozyme 1, mitochondrial； PDH kinase 1； mitochondrial pyruvate dehydrogenase, lipoamide, kinase isoenzyme 1； pyruvate dehydrogenase kinase, isoenzyme 1； 丙酮酸脱氢酶激酶1； 丙酮酸脱氢酶激酶同工酶1(PDK1)；
背景信息：
Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2013]
