基因名:
PAK2
产品别名:
PAK65; PAKgamma; PAK2; p21 (RAC1) activated kinase 2; p21 (RAC1) activated kinase 2; serine/threonine-protein kinase PAK 2; PAK-2; S6/H4 kinase; gamma-PAK; p21 (CDKN1A)-activated kinase 2; p21 protein (Cdc42/Rac)-activated kinase 2; p21-activated kinase 2; p58; p21激活激酶2; p21蛋白激活激酶2(PAK2); 磷酸化p21激活激酶2;
背景信息:
The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase mediated apoptosis, PAK2 also interacts with and is activated by HIV1 Nef.