重组蛋白二硫化物异构酶A2(PDI)

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重组蛋白二硫化物异构酶A2(PDI)

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

重组蛋白二硫键异构酶(PDI)
Recombinant P4HB

基因名：

P4HB

产品别名：

CLCRP1； DSI； ERBA2L； GIT； P4Hbeta； PDI； PDIA1； PHDB； PO4DB； PO4HB； PROHB； P4HB； prolyl 4-hydroxylase subunit beta； prolyl 4-hydroxylase subunit beta； protein disulfide-isomerase； cellular thyroid hormone-binding protein； collagen prolyl 4-hydroxylase beta； glutathione-insulin transhydrogenase； p55； procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), beta polypeptide； prolyl 4-hydroxylase, beta polypeptide； protein disulfide isomerase family A, member 1； protein disulfide isomerase-associated 1； protein disulfide isomerase/oxidoreductase； protocollagen hydroxylase； testicular secretory protein Li 32； thyroid hormone-binding protein p55；蛋白二硫化物异构酶A2(PDI)；蛋白二硫键异构酶(PDI)；蛋白质二硫键异构酶；

背景信息：

Protein Disulfide-Isomerase (P4HB) is an endoplasmic reticulum lumen protein that belongs to the protein disulfide isomerase family. P4HB contains two thioredoxin domains and catalyzes the formation, breakage, and rearrangement of -S-S- bonds in proteins. P4HB is involved in hydroxylation of prolyl residues in preprocollagen. P4HB has the ability to act as a chaperone that inhibits aggregation of misfolded proteins in a concentration-dependent manner. P4HB plays a role in both the influx and efflux of S-nitrosothiol-bound nitric oxide.