基因名：
P4HA1
产品别名：
P4HA； P4HA1； prolyl 4-hydroxylase subunit alpha 1； prolyl 4-hydroxylase subunit alpha 1； prolyl 4-hydroxylase subunit alpha-1； C-P4Halpha(I)； collagen prolyl 4-hydroxylase alpha(I)； procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide I； procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-1； prolyl 4-hydroxylase, alpha polypeptide I； 4-羟化酶α1； 脯氨酸-4-羟化酶α多肽Ⅰ(P4Ha1)；
背景信息：
This gene encodes a component of prolyl 4-hydroxylase, a key enzyme in collagen synthesis composed of two identical alpha subunits and two beta subunits. The encoded protein is one of several different types of alpha subunits and provides the major part of the catalytic site of the active enzyme. In collagen and related proteins, prolyl 4-hydroxylase catalyzes the formation of 4-hydroxyproline that is essential to the proper three-dimensional folding of newly synthesized procollagen chains. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
