基因名：
NR4A2
产品别名：
HZF-3； IDLDP； NOT； NURR1； RNR1； TINUR； NR4A2； nuclear receptor subfamily 4 group A member 2； nuclear receptor subfamily 4 group A member 2； nuclear receptor subfamily 4 group A member 2； NGFI-B/nur77 beta-type transcription factor homolog； T-cell nuclear receptor NOT； immediate-early response protein NOT； intermediate-early receptor protein； nuclear receptor related 1； nur related protein-1, human homolog of； orphan nuclear receptor NR4A2； orphan nuclear receptor NURR1； transcriptionally inducible nuclear receptor related 1； transcriptionally-inducible nuclear receptor； 核受体相关因子-1； 核受体相关蛋白1(NURR1)；
背景信息：
Nuclear receptor and transcription factor; plays a role in development and maintenance of neurons synthesizing the neurotransmitter dopamine This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. The encoded protein may act as a transcription factor. Mutations in this gene have been associated with disorders related to dopaminergic dysfunction, including Parkinson disease, schizophernia, and manic depression. Misregulation of this gene may be associated with rheumatoid arthritis. Four transcript variants encoding four distinct isoforms have been identified for this gene. Additional alternate splice variants may exist, but their full length nature has not been determined.
