基因名：
NME2
产品别名：
NDKB； NDPK-B； NDPKB； NM23-H2； NM23B； PUF； NME2； NME/NM23 nucleoside diphosphate kinase 2； NME/NM23 nucleoside diphosphate kinase 2； nucleoside diphosphate kinase B； HEL-S-155an； NDP kinase B； c-myc purine-binding transcription factor PUF； c-myc transcription factor； epididymis secretory sperm binding protein Li 155an； histidine protein kinase NDKB； non-metastatic cells 2, protein (NM23) expressed in； non-metastatic cells 2, protein (NM23B) expressed in； nucleotide diphosphate kinase B； 肿瘤抑制基因NME2； 非转移细胞2表达NM23A蛋白(NME2)；
背景信息：
NM23 is a heterodimeric protein functioning as a nucleoside diphosphate (NDP) kinase. NME1 and NME2 comprise the 152 amino acid A and B polypeptide chains of the NM23 enzyme, respectively. NME2 is identical to the beta subunit of human erythrocyte NDP kinase. NDP kinases are involved in the synthesis of nucleoside triphosphates, and NM23 may act in the regulation of signal transduction by complexing with G proteins, causing activation/inactivation of developmental pathways. NEM2 has been identified as a putative tumor suppressor. High expression of mouse NME2 is detected in heart, liver, and kidney, with moderate expression in skeletal muscle, and negligible expression in other mouse tissues examined.
