基因名:
NEO1
产品别名:
IGDCC2; NGN; NTN1R2; NEO1; neogenin 1; neogenin 1; neogenin; immunoglobulin superfamily DCC subclass member 2; neogenin homolog 1; 再生蛋白1(NEO1); 神经细胞粘附蛋白NGN;
背景信息:
This gene encodes a cell surface protein that is a memberof the immunoglobulin superfamily. The encoded protein consists offour N-terminal immunoglobulin-like domains, six fibronectin typeIII domains, a transmembrane domain and a C-terminal internaldomain that shares homology with the tumor suppressor candidategene DCC. This protein may be involved in cell growth anddifferentiation and in cell-cell adhesion. Defects in this gene areassociated with cell proliferation in certain cancers. Alternatesplicing results in multiple transcript variants. [provided byRefSeq, Feb 2010].