基因名:
NEDD4
产品别名:
NEDD4-1; RPF1; NEDD4; NEDD4 E3 ubiquitin protein ligase; NEDD4 E3 ubiquitin protein ligase; E3 ubiquitin-protein ligase NEDD4; HECT-type E3 ubiquitin transferase NEDD4; cell proliferation-inducing gene 53 protein; neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase; receptor-potentiating factor 1; 神经前体细胞发育下调蛋白4;
背景信息:
NEDD4 (neural precursor cell expressed developmentally down-regulated protein 4) is a widely expressed HECT domain-containing E3 ubiquitin ligase. NEDD4 ubiquitinates a few membrane proteins, including IGF-1R and PTEN, by which it regulates signal transduction.