基因名:
MMP10
产品别名:
SL-2; STMY2; MMP10; matrix metallopeptidase 10; matrix metallopeptidase 10; stromelysin-2; MMP-10; matrix metalloprotease 10; matrix metalloproteinase 10 (stromelysin 2); matrix metalloproteinase-10; transin 2; 基质金属蛋白酶-10; 基质金属蛋白酶10(MMP10);
背景信息:
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans and fibronectin. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.