基因名：
MMP9
产品别名：
CLG4B； GELB； MANDP2； MMP-9； MMP9； matrix metallopeptidase 9； matrix metallopeptidase 9； matrix metalloproteinase-9； macrophage gelatinase； matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)； matrix metalloproteinase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)； type V collagenase； 基质金属蛋白酶-9； 基质金属蛋白酶-9蛋白； 基质金属蛋白酶9； 基质金属蛋白酶9(MMP9)； 基质金属蛋白酶9(MMP9)真核蛋白；
背景信息：
Matrix metallopeptidase 9 (MMP-9) is an enzyme encoded by the MMP9 gene. This protein, which is produced by normal alveolar macrophages and granulocytes, can be activated by 4-aminophenylmercuric acetate and phorbol ester and up-regulated by ARHGEF4, SPATA13 and APC via the JNK signaling pathway in colorectal tumor cells. MMP-9 is involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, angiogenesis, bone development, wound healing, cell migration, learning and memory, as well as in pathological processes, such as arthritis, intracerebral hemorrhage, and metastasis.
