基因名:
CXCL9
产品别名:
CMK; Humig; MIG; SCYB9; crg-10; CXCL9; C-X-C motif chemokine ligand 9; C-X-C motif chemokine ligand 9; C-X-C motif chemokine 9; chemokine (C-X-C motif) ligand 9; gamma-interferon-induced monokine; monokine induced by gamma interferon; monokine induced by interferon-gamma; small-inducible cytokine B9; γ干扰素诱导单核细胞因子; 干扰素γ诱导单核因子(MIg);
背景信息:
Chemokine (C-X-C Motif) Ligand 9 (CXCL9) belongs to the intercrine alpha (chemokine CXC) family. It is secreted by interferon stimulated monocytes, macrophages and endothelial cells, which elicits chemotactic functions by interacting with the chemokine receptor CXCR3. CXCL9 acts as a Th1 (type 1 helper T) cell chemoattractant and plays a role in the growth, activation and movement of cells associated with immune and inflammatory responses, and in tumour growth inhibition. It is closely related to two other CXC chemokines called CXCL10 and CXCL11, whose genes are located near the gene for CXCL9 on human chromosome 4.