基因名:
MICB
产品别名:
PERB11.2; MICB; MHC class I polypeptide-related sequence B; MHC class I polypeptide-related sequence B; MHC class I polypeptide-related sequence B; MHC class I antigen-related protein B; MHC class I chain-related protein B; MHC class I mic-B antigen; MHC class I-like molecule PERB11.2-IMX; stress inducible class I homolog; MICB蛋白; Ⅰ类MHC多肽相关序列B(MICB);
背景信息:
This protein is a heavily glycosylated protein which is a ligand for the NKG2D type II receptor. Binding of the ligand activates the cytolytic response of natural killer (NK) cells, CD8 alphabeta T cells, and gammadelta T cells which express the receptor. This protein is stress-induced and is similar to MHC class I molecules; however, it does not associate with beta-2-microglobulin or bind peptides. Alternative splicing results in multiple transcript variants.