基因名:
ADAM11
产品别名:
MDC; ADAM11; ADAM metallopeptidase domain 11; ADAM metallopeptidase domain 11; disintegrin and metalloproteinase domain-containing protein 11; ADAM 11; metalloproteinase-like, disintegrin-like, and cysteine-rich protein; 去整合素样金属蛋白酶11;
背景信息:
This gene encodes a member of the ADAM (a disintegrin and metalloprotease) protein family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This gene represents a candidate tumor supressor gene for human breast cancer based on its location within a minimal region of chromosome 17q21 previously defined by tumor deletion mapping. [provided by RefSeq, Jul 2008].