基因名：
MCM2
产品别名：
BM28； CCNL1； CDCL1； D3S3194； DFNA70； MITOTIN； cdc19； MCM2； minichromosome maintenance complex component 2； minichromosome maintenance complex component 2； DNA replication licensing factor MCM2； cell devision cycle-like 1； cyclin-like 1； minichromosome maintenance deficient 2 (mitotin)； minichromosome maintenance protein 2 homolog； nuclear protein BM28； 微小染色体维持缺陷蛋白2； 微小染色体维持缺陷蛋白2(MCM2)； 磷酸化MCM2蛋白；
背景信息：
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined. [provided by RefSeq, Oct 2012]
