基因名:
MAGEA6
产品别名:
CT1.6; MAGE-3b; MAGE3B; MAGE6; MAGEA6; MAGE family member A6; MAGE family member A6; melanoma-associated antigen 6; MAGE-6 antigen; MAGE3B antigen; cancer/testis antigen 1.6; cancer/testis antigen family 1, member 6; melanoma antigen family A, 6; melanoma antigen family A6; 黑色素瘤相关抗原6;
背景信息:
This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]