基因名：
NBR1
产品别名：
1A1-3B； IAI3B； M17S2； MIG19； NBR1； NBR1 autophagy cargo receptor； NBR1 autophagy cargo receptor； next to BRCA1 gene 1 protein； B-box protein； cell migration-inducing gene 19 protein； membrane component, chromosome 17, surface marker 2 (ovarian carcinoma antigen CA125)； migration-inducing protein 19； neighbor of BRCA1 gene 1； 细胞迁移诱导蛋白19；
背景信息：
The protein encoded by this gene was originally identified as an ovarian tumor antigen monitored in ovarian cancer. The encoded protein contains a B-box/coiled-coil motif, which is present in many genes with transformation potential. It functions as a specific autophagy receptor for the selective autophagic degradation of peroxisomes by forming intracellular inclusions with ubiquitylated autophagic substrates. This gene is located on a region of chromosome 17q21.1 that is in close proximity to the BRCA1 tumor suppressor gene. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2014]
