基因名:
KRT7
产品别名:
CK7; K2C7; K7; SCL; KRT7; keratin 7; keratin 7; keratin, type II cytoskeletal 7; CK-7; cytokeratin 7; keratin 7, type II; keratin, 55K type II cytoskeletal; keratin, simple epithelial type I, K7; sarcolectin; type II mesothelial keratin K7; type-II keratin Kb7; 细胞角蛋白7; 角蛋白7(CK7);
背景信息:
Keratins are a large family of proteins that form the intermediate filament cytoskeleton of epithelial cells,which are classified into two major sequence types. Type I keratins are a group of acidic intermediate filament proteins,including K9–K23,and the hair keratins Ha1–Ha8. Type II keratins are the basic or neutral courterparts to the acidic type I keratins,including K1–K8,and the hair keratins,Hb1–Hb6. KRT7,also named as cytokeratin 7,is one member of type II basic cytokeratin. It is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels,and their neoplasms. KRT7 is marker of epithelial tissues,but not present in carcinomas of stratified squamous cell origin.This antibody is specifically against KRT7.