基因名:
KPNA2
产品别名:
IPOA1; PTAC58; QIP2; RCH1; SRP1-alpha; SRP1alpha; KPNA2; karyopherin subunit alpha 2; karyopherin subunit alpha 2; importin subunit alpha-1; RAG cohort protein 1; importin subunit alpha-2; importin-alpha-P1; karyopherin alpha 2 (RAG cohort 1, importin alpha 1); nuclear pore-targeting complex 58kD component; pendulin; 亲核素α2(KPNa2); 核蛋白2;
背景信息:
Karyopherin Subunit α-2 (KPNA2) belongs to the importin alpha family. KPNA2 is widely expressed in many tissues and contains an N-terminal hydrophilic region, a hydrophobic central region composed of 10 repeats, and a short hydrophilic C-terminus. KPNA2 interacts with the NLSs of DNA helicase Q1 and SV40 T antigen and may be involved in the nuclear transport of proteins. KPNA2 also may play a role in V(D)J recombination. KPNA2 functions in nuclear protein importantly as an adapter protein for nuclear receptor KPNB1.