重组钾离子通道蛋白家族KCNQ1

首页蛋白库基因库产品会员服务

位置：首页 > 产品库 > 重组钾离子通道蛋白家族KCNQ1

立即咨询

重组钾离子通道蛋白家族KCNQ1

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

Recombinant KCNQ1
Recombinant potassium voltage-gated channel subfamily Q member 1 protein

基因名：

KCNQ1

产品别名：

ATFB1； ATFB3； JLNS1； KCNA8； KCNA9； KVLQT1； Kv1.9； Kv7.1； LQT； LQT1； RWS； SQT2； WRS； KCNQ1； potassium voltage-gated channel subfamily Q member 1； potassium voltage-gated channel subfamily Q member 1； potassium voltage-gated channel subfamily KQT member 1； IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1； kidney and cardiac voltage dependend K+ channel； potassium channel, voltage gated KQT-like subfamily Q, member 1； potassium voltage-gated channel, KQT-like subfamily, member 1； slow delayed rectifier channel subunit； voltage-gated potassium channel subunit Kv7.1；钾离子通道蛋白家族KCNQ1；

背景信息：

Probably important in cardiac repolarization. Associates with KCNE1 (MinK) to form the I(Ks) cardiac potassium current. Elicits a rapidly activating, potassium-selective outward current. Muscarinic agonist oxotremorine-M strongly suppresses KCNQ1/KCNE1 current in CHO cells in which cloned KCNQ1/KCNE1 channels were coexpressed with M1 muscarinic receptors. May associate also with KCNE3 (MiRP2) to form the potassium channel that is important for cyclic AMP-stimulated intestinal secretion of chloride ions, which is reduced in cystic fibrosis and pathologically stimulated in cholera and other forms of secretory diarrhea. Involvement in disease: