重组电压门控钾通道Kv1,2蛋白

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重组电压门控钾通道Kv1,2蛋白

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Recombinant KCNA2
Recombinant potassium voltage-gated channel subfamily A member 2 protein

基因名：

KCNA2

产品别名：

DEE32； EIEE32； HBK5； HK4； HUKIV； KV1.2； MK2； NGK1； RBK2； KCNA2； potassium voltage-gated channel subfamily A member 2； potassium voltage-gated channel subfamily A member 2； potassium voltage-gated channel subfamily A member 2； potassium channel, voltage gated shaker related subfamily A, member 2； potassium voltage-gated channel, shaker-related subfamily, member 2； voltage-gated K(+) channel HuKIV； voltage-gated potassium channel HBK5； voltage-gated potassium channel protein Kv1.2； voltage-gated potassium channel subunit Kv1.2；电压门控钾通道Kv1.2；

背景信息：

Kv1.2 mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which K(+) ions may pass in accordance with their electrochemical gradient. Kv1.2 binds PDZ domains of DLG1, DLG2 and DLG4. The N-terminus may be important in determining the rate of inactivation of the channel while the tail may play a role in modulation of channel activity and/or targeting of the channel to specific subcellular compartments.