基因名:
JUP
产品别名:
CTNNG; DP3; DPIII; PDGB; PG; PKGB; JUP; junction plakoglobin; junction plakoglobin; junction plakoglobin; catenin (cadherin-associated protein), gamma 80kDa; desmoplakin III; desmoplakin-3; desmosomal protein 3; γ-连环素/连接蛋白γ; γ连环蛋白/Cateninγ/γ链接素; 磷酸化γ连环蛋白; 连接桥粒斑珠蛋白(JUP);
背景信息:
This gene encodes a major cytoplasmic protein which is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins and is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat. Mutation in this gene has been associated with Naxos disease. Alternative splicing occurs in this gene; however, not all transcripts have been fully described. [provided by RefSeq].