基因名:
ITIH3
产品别名:
H3P; ITI-HC3; SHAP; ITIH3; inter-alpha-trypsin inhibitor heavy chain 3; inter-alpha-trypsin inhibitor heavy chain 3; inter-alpha-trypsin inhibitor heavy chain H3; ITI heavy chain H3; inter-alpha (globulin) inhibitor H3; inter-alpha (globulin) inhibitor, H3 polypeptide; inter-alpha-inhibitor heavy chain 3; pre-alpha (globulin) inhibitor, H3 polypeptide; serum-derived hyaluronan-associated protein; 中间α-球蛋白抑制因子H3(ITIH3);
背景信息:
ITIH3, which is short for Inter-alpha-trypsin inhibitor heavy chain H3, is a 890 aa. protein. It is secreted expression, and belongs to the ITIH family. I-alpha-I plasma protease inhibitors are assembled from one or two heavy chains (H1, H2 or H3) and one light chain, bikunin. Inter-alpha-inhibitor (I-alpha-I) is composed of H1, H2 and bikunin, inter-alpha-like inhibitor (I-alpha-LI) of H2 and bikunin, and pre-alpha-inhibitor (P-alpha-I) of H3 and bikunin. ITTH3 may act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to regulate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes.