基因名：
ITGAM
产品别名：
CD11B； CR3A； MAC-1； MAC1A； MO1A； SLEB6； ITGAM； integrin subunit alpha M； integrin subunit alpha M； integrin alpha-M； CD11 antigen-like family member B； CR-3 alpha chain； antigen CD11b (p170)； cell surface glycoprotein MAC-1 subunit alpha； complement component 3 receptor 3 subunit； integrin, alpha M (complement component 3 receptor 3 subunit)； leukocyte adhesion receptor MO1； macrophage antigen alpha polypeptide； macrophage-1 antigen alpha subunit； neutrophil adherence receptor alpha-M subunit； 整合素αM； 整合素αM(CD11b)； 整合素αM(CD11b)真核蛋白； 整合素αM/巨噬细胞表面分子；
背景信息：
This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
