基因名：
ITGA4
产品别名：
CD49D； IA4； ITGA4； integrin subunit alpha 4； integrin subunit alpha 4； integrin alpha-4； 269C wild type； CD49 antigen-like family member D； VLA-4 subunit alpha； alpha 4 subunit of VLA-4 receptor； antigen CD49D, alpha-4 subunit of VLA-4 receptor； integrin alpha-IV； very late activation protein 4 receptor, alpha 4 subunit； 整合素α4； 整合素α4(ITGa4)；
背景信息：
The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 4 subunit. This subunit associates with a beta 1 or beta 7 subunit to form an integrin that may play a role in cell motility and migration. This integrin is a therapeutic target for the treatment of multiple sclerosis, Crohn's disease and inflammatory bowel disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]
