基因名：
PDX1
产品别名：
GSF； IDX-1； IPF1； IUF1； MODY4； PAGEN1； PDX-1； STF-1； PDX1； pancreatic and duodenal homeobox 1； pancreatic and duodenal homeobox 1； pancreas/duodenum homeobox protein 1； IPF-1； IUF-1； glucose-sensitive factor； insulin promoter factor 1, homeodomain transcription factor； insulin upstream factor 1； islet/duodenum homeobox-1； pancreatic-duodenal homeobox factor 1； somatostatin transcription factor 1； somatostatin-transactivating factor 1； 胰岛素促进因子/胰十二指肠同源异型盒蛋白；
背景信息：
The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (IDDM), as well as maturity onset diabetes of the young type 4 (MODY4). [provided by RefSeq, Aug 2017]
