基因名:
ING1
产品别名:
p24ING1c; p33; p33ING1; p33ING1b; p47; p47ING1a; ING1; inhibitor of growth family member 1; inhibitor of growth family member 1; inhibitor of growth protein 1; growth inhibitor ING1; growth inhibitory protein ING1; tumor suppressor ING1; 生长抑制因子基因1;
背景信息:
This gene encodes a tumor suppressor protein that can induce cell growth arrest and apoptosis. The encoded protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of this gene have been detected in various cancers. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]