基因名：
IMPA1
产品别名：
IMP； IMPA； MRT59； IMPA1； inositol monophosphatase 1； inositol monophosphatase 1； inositol monophosphatase 1； D-galactose 1-phosphate phosphatase； IMP 1； IMPase 1； inositol(myo)-1(or 4)-monophosphatase 1； inositol-1(or 4)-monophosphatase 1； lithium-sensitive myo-inositol monophosphatase A1； myo-inositol monophosphatase 1； testicular tissue protein Li 94； 肌醇单磷酸酶1；
背景信息：
Inositol Monophosphatase 1 (IMPA1) belongs to the inositol monophosphatase family. IMPA1 is responsible for the provision of inositol required for synthesis of phosphatidylinositol and polyphosphoinositides, IMPA1 can use myo-inositol-1,3-diphosphate, myo-inositol-1,4-diphosphate, scyllo-inositol-phosphate, glucose-1-phosphate, glucose-6-phosphate, fructose-1-phosphate, beta-glycerophosphate, and 2-AMP as substrates. IMPA1 has been implicated as the pharmacological target for lithium action in brain. IMPA1 shows magnesium-dependent phosphatase activity and is inhibited by therapeutic concentrations of lithium. In addition, IMPA1 plays a improtant role in intracellular signal transduction.
