基因名：
IL3RA
产品别名：
CD123； IL3R； IL3RAY； IL3RX； IL3RY； hIL-3Ra； IL3RA； interleukin 3 receptor subunit alpha； interleukin 3 receptor subunit alpha； interleukin-3 receptor subunit alpha； CD123 antigen； IL-3 receptor subunit alpha； IL-3R subunit alpha； IL-3R-alpha； IL-3RA； interleukin 3 receptor, alpha (low affinity)； IL-3R alpha蛋白； 白介素3受体a（CD123）链； 白介素3受体α(IL3Ra)； 白介素3受体α(IL3Ra)真核蛋白；
背景信息：
CD123, also known as Interleukin-3 receptor subunit alpha, belongs to the type I cytokine receptor family. In mouse, there are two classes of high-affinity IL3 receptors. One contains an IL3-specific beta subunit and the other contains the beta subunit also shared by high-affinity IL5 and GM-CSF receptors. CD123 stimulates the proliferation and differentiation of hemopoietic cells including the pluripotent hematopoietic stem cells as well as various lineage-committed cells. CD123 is a heterodimer consisting of an alpha and a beta subunit. The alpha subunit alone binds IL-3 with low affinity. The beta subunit does not bind IL-3 by itself but is required for the high-affinity binding of IL-3 to the heterodimeric receptor complex.
