基因名：
RBPJ
产品别名：
AOS3； CBF-1； CBF1； IGKJRB； IGKJRB1； KBF2； RBP-J； RBP-J kappa； RBP-JK； RBPJK； RBPSUH； SUH； csl； RBPJ； recombination signal binding protein for immunoglobulin kappa J region； recombination signal binding protein for immunoglobulin kappa J region； recombining binding protein suppressor of hairless； H-2K binding factor-2； immunoglobulin kappa J region recombination signal binding protein 1； renal carcinoma antigen NY-REN-30； suppressor of hairless homolog； Notch转录调控蛋白RBPJK；
背景信息：
Transcriptional regulator that plays a central role in Notch signaling, a signaling pathway involved in cell-cell communication that regulates a broad spectrum of cell-fate determinations. Acts as a transcriptional repressor when it is not associated with Notch proteins. When associated with some NICD product of Notch proteins (Notch intracellular domain), it acts as a transcriptional activator that activates transcription of Notch target genes. Probably represses or activates transcription via the recruitment of chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins, respectively. Specifically binds to the immunoglobulin kappa-type J segment recombination signal sequence.
