基因名:
IGFBP1
产品别名:
AFBP; IBP1; IGF-BP25; PP12; hIGFBP-1; IGFBP1; insulin like growth factor binding protein 1; insulin like growth factor binding protein 1; insulin-like growth factor-binding protein 1; IBP-1; IGF-binding protein 1; IGFBP-1; alpha-pregnancy-associated endometrial globulin; amniotic fluid binding protein; binding protein-25; binding protein-26; binding protein-28; growth hormone independent-binding protein; placental protein 12; 胰岛素样生长因子结合蛋白1; 胰岛素样生长因子结合蛋白1(IGFBP1); 胰岛素样生长因子结合蛋白1(IGFBP1)真核蛋白;
背景信息:
Insulin-like growth factor-binding protein 1 (IGFBP1) is encoded by 259 amino acid (aa) with 25 aa residue signal peptide that is processed to generate the 234 aa residue mature protein. IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Promotes cell migration. Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs).