重组异柠檬酸脱氢酶1蛋白

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重组异柠檬酸脱氢酶1蛋白

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重组异柠檬酸脱氢酶1(IDH1)蛋白
Recombinant IDH1

基因名：

IDH1

产品别名：

HEL-216； HEL-S-26； IDCD； IDH； IDP； IDPC； PICD； IDH1； isocitrate dehydrogenase (NADP(+)) 1； isocitrate dehydrogenase (NADP(+)) 1； isocitrate dehydrogenase [NADP] cytoplasmic； NADP(+)-specific ICDH； NADP-dependent isocitrate dehydrogenase, cytosolic； NADP-dependent isocitrate dehydrogenase, peroxisomal； epididymis luminal protein 216； epididymis secretory protein Li 26； epididymis secretory sperm binding protein； isocitrate dehydrogenase (NADP(+)) 1, cytosolic； isocitrate dehydrogenase 1 (NADP+), soluble； oxalosuccinate decarboxylase；异柠檬酸脱氢酶1；异柠檬酸脱氢酶1(IDH1)；

背景信息：

Isocitrate Dehydrogenase [NADP] Cytoplasmic (IDH1) belongs to the isocitrate and isopropylmalate dehydrogenases family. IDH1 exists as a homodimer, binding one magnesium or manganese ion per subunit. Mutations of IDH1 have been shown to cause metaphyseal chondromatosis with aciduria and are involved in the development of glioma IDH plays a role in the regeneration of NADPH for intraperoxisomal reductions, such as the conversion of 2, 4-dienoyl-CoAs to 3-enoyl-CoAs, as well as in peroxisomal reactions that consume 2-oxoglutarate, namely the α-hydroxylation of phytanic acid.