基因名：
ID1
产品别名：
ID； bHLHb24； ID1； inhibitor of DNA binding 1, HLH protein； inhibitor of DNA binding 1, HLH protein； DNA-binding protein inhibitor ID-1； class B basic helix-loop-helix protein 24； dJ857M17.1.2 (inhibitor of DNA binding 1, dominant negative helix-loop-helix protein)； inhibitor of DNA binding 1, dominant negative helix-loop-helix protein； inhibitor of differentiation 1； DNA结合抑制因子1；
背景信息：
ID proteins contain a helix-loop-helix (HLH) motif and regulate tissue-specific transcription within several cell lineages. They do not bind DNA directly, but inhibit lineage commitment by binding basic helix-loop-helix (bHLH) transcription factors through their HLH motif. ID proteins contribute to cell growth, senescence, differentiation and angiogenesis. Id1 mRNA is highly expressed in heart, lung and kidney and has lower expression in brain and liver. Two transcript variants encoding different isoforms have been found for this gene.
