基因名:
IRF8
产品别名:
H-ICSBP; ICSBP; ICSBP1; IMD32A; IMD32B; IRF-8; IRF8; interferon regulatory factor 8; interferon regulatory factor 8; interferon regulatory factor 8; interferon consensus sequence binding protein 1; 干扰素调节因子8; 干扰素调节因子8(IRF8);
背景信息:
Interferon consensus sequence-binding protein (ICSBP) is a transcription factor of the interferon (IFN) regulatory factor (IRF) family. Proteins of this family are composed of a conserved DNA-binding domain in the N-terminal region and a divergent C-terminal region that serves as the regulatory domain. The IRF family proteins bind to the IFN-stimulated response element (ISRE) and regulate expression of genes stimulated by type I IFNs, namely IFN-alpha and IFN-beta. IRF family proteins also control expression of IFN-alpha and IFN-beta-regulated genes that are induced by viral infection. [provided by RefSeq, Jul 2008]