基因名:
ICAM3
产品别名:
CD50; CDW50; ICAM-R; ICAM3; intercellular adhesion molecule 3; intercellular adhesion molecule 3; intercellular adhesion molecule 3; ICAM-3; 细胞间粘附分子3; 细胞间粘附分子3(ICAM3);
背景信息:
This protein is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule.