基因名:
TNC
产品别名:
150-225; DFNA56; GMEM; GP; HXB; JI; TN; TN-C; TNC; tenascin C; tenascin C; tenascin; GP 150-225; cytotactin; deafness, autosomal dominant 56; glioma-associated-extracellular matrix antigen; hexabrachion (tenascin); myotendinous antigen; neuronectin; tenascin-C additional domain 1; 细胞粘合素(固生蛋白); 细胞粘合素(固生蛋白)蛋白; 细胞粘合素/腱糖蛋白-C/固生蛋白; 肌腱蛋白C(TNC); 腱糖蛋白R;
背景信息:
Tenascin-C (TNC) is a hexameric, multimodular extracellular matrix protein with several molecular forms that are created through alternative splicing and protein modifications. It is highly conserved amongst vertebrates, and molecular phylogeny indicates that it evolved before fibronectin. Tenascin-C has many extracellular binding partners, including matrix components, soluble factors and pathogens; it also influences cell phenotype directly through interactions with cell surface receptors.