基因名:
HRH2
产品别名:
H2R; HH2R; HRH2; histamine receptor H2; histamine receptor H2; histamine H2 receptor; gastric receptor 1; gastric receptor I; 组胺受体H2;
背景信息:
The HRH2 subclass of histamine receptors mediates gastric acid secretion. Also appears to regulate gastrointestinal motility and intestinal secretion. Possible role in regulating cell growth and differentiation. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and, through a separate G protein-dependent mechanism, the phosphoinositide/protein kinase (PKC) signaling pathway.