基因名：
ERAS
产品别名：
HRAS2； HRASP； ERAS； ES cell expressed Ras； ES cell expressed Ras； GTPase ERas； E-Ras； embryonic stem cell-expressed Ras； small GTPase protein E-Ras； v-Ha-ras Harvey rat sarcoma viral oncogene homolog 2； v-Ha-ras Harvey rat sarcoma viral oncogene homolog pseudogene； 胚胎干细胞RAS蛋白；
背景信息：
ERAS belongs to the small GTPase superfamily. Ras family. Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. The ERas gene is expressed in embryonic stem (ES) cells and promotes their in vitro proliferation and tumorigenicity. ERas-null ES cells maintain pluripotency but show significantly reduced growth and tumorigenicity, which are rescued by expression of ERas complementary DNA or by activated phosphatidylinositol-3-OH kinase.
