基因名：
HNF4A
产品别名：
FRTS4； HNF4； HNF4a7； HNF4a8； HNF4a9； HNF4alpha； MODY； MODY1； NR2A1； NR2A21； TCF； TCF-14； TCF14； HNF4A； hepatocyte nuclear factor 4 alpha； hepatocyte nuclear factor 4 alpha； hepatocyte nuclear factor 4-alpha； HNF4A wild type； HNF4alpha10/11/12； hepatic nuclear factor 4 alpha； nuclear receptor subfamily 2 group A member 1； transcription factor 14； transcription factor HNF-4； 磷酸化肝细胞核因子4α； 肝细胞核因子4α； 肝细胞核因子4α(HNF4a)；
背景信息：
The protein encoded by the HNF4 gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non insulin dependent diabetes mellitus type I. At least three different transcript variants encoding three different isoforms have been found for this gene.
